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Healthcare Directory—Christopher T. Ritchlin MD

Last directory upload February-23-2020

Christopher T. Ritchlin MD

Christopher T. Ritchlin MD

Allergy & Immunology
Internal Medicine, Rheumatology

Medical School / Professional School:
Albany Medical College

American Board of Internal Medicine
American Board of Internal Medicine-Rheumatology

Dr. Ritchlin's basic science research efforts are directed towards understanding the mechanisms that underlie pathologic bone resorption and new bone formation in psoriatic arthritis and rheumatoid arthritis. Using a translational approach, investigators in his lab are analyzing the cell surface molecules expressed by osteoclast and dendritic cell precursors with the goal to identify susceptibility and response biomarkers in patients with inflammatory arthritis. The lab is also studying the effect of anti-TNF agents on dendritic cell differentiation in RA and PsA patients. In addition, collaborative studies are underway with the lab of Dr. Eddie Schwarz to understand the mechanisms that are responsible for bone marrow edema as recorded on magnetic resonance imaging scans in inflammatory arthritis. The bulk of this work is performed in animal models but insights gained from these studies are applied to the study of human joint diseases such as psoriatic and rheumatoid arthritis. Dr. Ritchlin is also the Director of the Clinical Immunology Research Unit where he is the principle investigator on several clinical trials testing the efficacy of anti-TNF agents and other biologic molecules in the treatment of psoriatic and rheumatoid arthritis and ankylosing spondylitis. In the Clinical Immunology Research Unit, patient oriented research is conducted on multiple levels. Investigator New Drug (IND) trials of novel agents (adalimumab, rituximab) in the treatment of PsA and AS have been completed or are about to start. Additional trials have been performed to study the effect of TNF inhibition on the frequency of osteoclast precursors and enhancing bone marrow edema in PsA. The Unit also conducts multicenter trials with novel biologic agents such as rituximab and abatacept in PsA with special attention directed towards understanding how these agents alter bone remodeling in these disorders. Additional studies underway include microanalysis assays of synovium, skin and intestinal tissues in patients with Immune Mediated Inflammatory Disroders (IMIDs) before and after TNF inhibition. Future plans include the development of ultrasound outcome measures in collaboration with Dr. Ralf Thiele and Dr. Darren Tabechian, to assess synovial, lymph node and periarticular tissue responses to different therapies in inflammatory arthritis.


Strong Allergy Immunology Rheumatology

4901 Lac De Ville Blvd. Suite 240
Rochester New York 14618
Monroe County
Phone: 585-341-7900
Fax:      585-340-5399

Location Comments: The University of Rochester Medical Center's Division of Allergy, Immunology, and Rheumatology has a long history, dating back to the late 1950s, of providing excellence in patient care, medical research, and education. Our current physicians, scientists, and staff are committed to carrying on this tradition. To these ends, we strive to provide timely, individualized, state-of-the-art medical care to patients with musculoskeletal, autoimmune, and allergic diseases. Through our research, we seek to expand our understanding of the mechanisms that underlie these disorders, with the goal of developing more effective and less toxic treatments. Lastly, by educating health care providers and acting as advocates for our patients, we seek to improve their treatment outcomes and the quality of their lives.

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Strong Memorial Hospital (Allergy-Immunology-Rheumatologgy)

400 Red Creek Drive Suite 240
Rochester New York 14623
Monroe County
Phone: 585-486-0901
Fax:      585-340-5399

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Strong Memorial Hospital (Allergy-Immunology-Rheumatologgy)

125 Lattimore Road Suite G-110
Rochester New York 14620
Monroe County
Phone: 585-486-0901
Fax:      585-340-5399

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